Publications

Molecular & Cellular Proteomics

Abstract

Perlecan is a critical proteoglycan found in the extracellular matrix (ECM) of cartilage. In healthy cartilage, perlecan regulates cartilage biomechanics and we...

Nature Methods

Abstract

Single-molecule localization microscopy is a powerful tool for visualizing subcellular structures, interactions and protein functions in biological research. However, inhomogeneo...

Connective Tissue Research

Abstract

Osteoarthritis (OA) is typically managed in late stages by replacement of the articular cartilage surface with a prosthesis as an effective, though undesirable outcom...

Journal of Biological Engineering

Abstract

Metabolic labeling of proteins with non-canonical amino acids (ncAAs) provides unique bioorthogonal chemical groups during de novo synthesis by taking advantag...

Experimental Mechanics

Abstract

Cells directly interact with the extracellular matrix (ECM) in their microenvironment; however, the mechanical properties of the networks at this scale are not well defin...

Journal of Biomechanical Engineering

Abstract

During chondrogenesis, tissue organization changes dramatically. We previously showed that the compressive moduli of chondrocytes increase concomitantly wit...

Acta Biomaterialia

Abstract

Vocal fold scarring is the fibrotic manifestation of a variety of voice disorders, and is difficult to treat. Tissue engineering therapies provide a potential strategy to reg...

Acta Biomaterialia

Abstract

Volumetric muscle loss (VML) occurs when skeletal muscle injury is too large for the body to fully self-repair. Typically, fibrotic tissue fills the void, which reduces muscl...

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Address

University of Colorado - Boulder

1111 Engineering Drive
UCB 427
Boulder, Colorado 80309-0427

Contact

Phone: 765 496-1768

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