MEML
NEWs
July 07, 2020
Andrea succesfully defends her PhD!
CHARACTERIZING THE MECHANICAL BEHAVIOR OF EXTRACELLULAR MATRIX NETWORKS IN SITU
June 16, 2020
Aya succesfully defends her PhD!
PROBING PROTEIN DYNAMICS IN VIVO USING NONCANONICAL
AMINO ACID LABELING
May 27, 2020
Chenwei's paper is accepted for publication in The Laryngoscope!
Restricted Water Intake Adversely Affects Rat Vocal Fold Biology - investigated in collaboration with Preeti Sivasankar and Abby Cox. Great work everyone!
May 14, 2020
Our collaborators at the Solorio lab just got their paper accepted in Cancers!
The Dynamic Relationship of Breast Cancer Cells and Fibroblasts in Fibronectin Accumulation at Primary and Metastatic Tumor Sites.
It was great to work with Sarah Libring and Luis and get some pretty pictures of newly synthesized ECM
April 20, 2020
Alita succesfully defends her master's thesis! Congratulations!
Extracellular Matrix Dynamics in Skeletal Muscle Hypertrophy for Regenerative Therapies
March 19, 2020
Fan, Donghan and Fang developed INSPR, beautiful method that uses super-resolution microscopy to resolve many subcellular structures, as well as the ECM within tissues! Coming soon to Nature Methods.
March 04, 2020
Alex succesfully defends his master's thesis - congratulations!
Excellent job describing how perlecan knockdown affect the proteome of developing cartilage!
January 05, 2020
Aya is recognized as a "shooting star" at CMBE 2020!
She gave a great talk on "Probing the Dynamics of Extracellular Matrix Proteins in the Developing Mouse" in beautiful Puerto Rico.
November 22, 2019
Kaitlin's paper is accepted for publication in Connective Tissue Research!
A collaborative review with the Neu Lab
November 14, 2019
Alita travels to CA to present her research at ABRCMS 2019!
November 08, 2019
Sarah Lipp gave an excellent talk at ASN Kidney week!
Work done with our great collaborators David Hains and Andrew Schwaderer @IUSM: Mass spectrometric analysis of the extracellular matrix during renal development
August 09, 2019
Aya's paper is accepted in CMBE!
Dynamics of non-canonical amino acid-labeled intra- and extracellular proteins in the developing mouse
August 06, 2019
Ye's collaboration with the Huang lab can now be found on bioRxiv
"Three dimensional nanoscopy of whole cells and tissues with in situ point spread function retrieval" used to look at the extracellular matrix of cartilage! Thank you for including us in your study (and for showing a similar appreciation of the ECM), Fang!
July 26, 2019
Sarah Lipp is awarded an ICT Fellowship!
The Innovation for Clinical Translation (ICT) Fellowship program was established as a key component of the expanding partnership between the Purdue College of Engineering and Indiana University School of Medicine to increase the number of doctoral engineering students who are focused on translating innovating technologies to clinical practice.
June 10, 2019
Julian starts his Master's studies in the MEML - Welcome to graduate school!
June 01, 2019
MEML collaborator, Adrian Buganza-Tepole, is awarded a grant from the NSF!
We are excited to help the Buganza Lab solve "Multiscale Mechanobiology of Growth and Remodeling During Wound Healing"
May 30, 2019
Aya is awarded a Truitt Fellowship! Congratulations!
The Truitt Fellowship is for Weldon School of Biomedical Engineering graduate students demonstrating superior academic achievements and scholarly abilities.
May 13, 2019
Alita graduates and continues her studies as a master's student! Congratulations on the promotion!
April 23, 2019
Andrea is recognized for her contributions to BME with an Outstanding Service Scholarship! Congratulations!
The Outstanding Service Scholarship recipients were selected by faculty in their School for their contributions to the quality, reputation, or success of the graduate student community, School, College, and/or University. Andrea was presented with the award at the CoE Awards Luncheon.
April 11, 2019
Aya and Tami's paper is accepted as part of the Journal of Biological Engineering's Emerging Leaders special issue!
It was great working with you, as well as Kristen and Brad from the Bundy Biotech Lab @ BYU. Congrats to all!
February 24, 2019
Andrea's paper is accepted at Experimental Mechanics! Great work Andrea and Sydney!
In situ measurement of native extracellular matrix strain
January 28, 2019
Tanaya's paper is accepted for publication at Acta Biomaterialia! Congratulations!
Incorporation of types I and III collagen in tunable hyaluronan hydrogels for vocal fold tissue engineering
A collaborative effort with the Sivasankar and Panitch labs
November 19, 2018
Congrats to Juan Martin for getting his paper accepted in Acta Biomaterialia!
Functionalization of hyaluronic acid hydrogels with ECM-derived peptides to control myoblast behavior
September 10, 2018
Andrea's back from her summer internship at AMGEN in South San Fransisco!
Andrea's work focused on using image analysis to study the 3D spatial distriubtion of tumor infiltrating lymphocytes in a mouse model.
August 17, 2018
Yue's paper is accepted for publication in Matrix Biology!
Hyaluronic Acid, CD44 and RHAMM regulate myoblast behavior during embryogenesis
August 03, 2018
Nick wins best bioenginering presentation at the SURF summer symposium!
Characterization and Quantification of Fibrin Gel Mechanics with Fibroblast Invasion - In collaboration with Adrian Buganza-Tepole in ME
April 06, 2018
Alex Ocken wins 2018 BME-IBSc-PI4D Research Symposium Poster Presentation
Award presented in category for Biomaterials, Biomechanics, and Tissue Engineering for poster titled: Quantifying Extracellular Matrix Protein Turnover In Vivo During Wound Healing.
February 01, 2018
Ye Bu joins MEML as a Post Doctoral Research Fellow
January 03, 2018
Dr. Calve awarded the Rising Star Award for Junior Faculty
Sarah Calve, an assistant professor in Purdue's Weldon School of Biomedical Engineering, has been named the recipient of the 2018 Rising Star Award for Junior Faculty from the Biomedical Engineering Society (BMES) at the Cellular and Molecular Bioengineering (CMBE) Conference on Jan. 3, in Key Largo, FL. The theme of this year’s conference was Transformative and Translational Mechanobiology.
December 01, 2018
Michael Walls begins his role as Research Associate in MEML
November 28, 2017
Andrea Acuña awarded the Ronald W. Dollens Graduate Scholarship
Andrea Acuña is a recipient of the Ronald W. Dollens Scholarship for 2017-2018. The scholarship is a joint award between the Weldon School of Biomedical Engineering and the College of Pharmacy, and is awarded based on academic merit to deserving PhD students in these schools who are performing research in the areas of cardiovascular devices, implantable biomaterials design, drug-delivery systems, or biochemical sensors.
September 30, 2017
MEML receives DP2 for Defining the Mechanical Link that Unites the Musculoskeletal System during Limb Development
Sarah Calve, assistant professor at Purdue's Weldon School of Biomedical Engineering, received the National Institutes of Health Director's New Innovator Award. The High-Risk, High-Reward Research Program award supports exceptionally creative scientists using highly innovative approaches to tackle major challenges in biomedical research. the musculoskeletal system from being primarily structural to one that is also instructive.
September 01, 2017
MEML receives R01 for Biomechanical Influence of ECM Remodeling on the Developing Enthesis
Our objective is to determine the composition, structure and mechanical properties of the extracellular matrix in the developing enthesis. The innovation of this proposal is the combination of bioorthogonal labeling, 3D imaging and atomic force microscopy-based mechanical analyses of viable murine tissues to characterize the developing enthesis as a function of development and embryonic motility. By characterizing the environment that facilitates enthesis assembly in vivo, the design of scaffolds and other regenerative therapies will be better informed and ultimately more successful.
August 01, 2017
Chenwei Duan joins MEML as a Graduate Research Assistant
July 01, 2016
MEML receives Showalter Trust award
Calve’s award will fund her research project entitled: “Design of 3D Hydrogels for the Treatment of Volumetric Muscle Loss.” The objective of this project is to identify and characterize hydrogel-peptide combinations that foster scar-free muscle repair after injury.
April 01, 2016
MEML Receives R21 for Bioorthogonal Labeling of Extracellular Matrix Assembly
Our objective is to metabolically label the extracellular matrix in developing tissues to identify key components and their rate of turnover. The innovation of this proposal is the combination of novel 3D imaging techniques and mass spectroscopy with bioorthogonal labeling of murine tissues in vivo to obtain a 4D map of ECM remodeling in the developing limb. By characterizing the environment that facilitates tissue assembly in vivo, the design of artificial scaffolds and other regenerative therapies will be better informed and ultimately more successful.
January 26, 2017
Alexander Ocken gets promoted
Alex Ocken joined the MEML as an undergrad in the Fall of 2015 and was instrumental in laying the groundwork for our non-canonical amino acid studies. We are happy that Alex decided to continue his graduate studies with the MEML, becoming a PhD student as of January 2017.
October 02, 2016
BMES podium presentations
Congrats to Andrea Acuna and Michael Drakopoulos for having their abstracts chosen for podium presentations at BMES 2016
Measurement of Displacement Fields of Native Extracellular Matrix Fibrils Loaded In Situ
Andrea Acuna
Michael Drakopoulos
Benjamin Sather
Craig Goergen
Sarah Calve
A Method to Characterize Extracellular Matrix Composition and 3D Structure During Embryonic Development
Michael Drakopoulos