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October 29, 2020

Sarah Lipp is a 2020 BioArt winner!

FASEB BioArt Scientific Image & Video Competition

July 07, 2020

Andrea succesfully defends her PhD!


June 16, 2020

Aya succesfully defends her PhD!



May 27, 2020

Chenwei's paper is accepted for publication in The Laryngoscope!

Restricted Water Intake Adversely Affects Rat Vocal Fold Biology - investigated in collaboration with Preeti Sivasankar and Abby Cox. Great work everyone!

May 15, 2020

Sarah Lipp passes her prelim exam!

Sarah is now officially a PhD candidate! Congratulations!

May 14, 2020

Our collaborators at the Solorio lab just got their paper accepted in Cancers!

The Dynamic Relationship of Breast Cancer Cells and Fibroblasts in Fibronectin Accumulation at Primary and Metastatic Tumor Sites. 

It was great to work with Sarah Libring and Luis and get some pretty pictures of newly synthesized ECM

May 07, 2020

Alex's paper is accepted for publication in Molecular and Cellular Proteomics!

Perlecan knockdown significantly alters extracellular matrix composition and organization during cartilage development

April 20, 2020

Alita succesfully defends her master's thesis! Congratulations!

Extracellular Matrix Dynamics in Skeletal Muscle Hypertrophy for Regenerative Therapies

March 19, 2020

Fan, Donghan and Fang developed INSPR, beautiful method that uses super-resolution microscopy to resolve many subcellular structures, as well as the ECM within tissues! Coming soon to Nature Methods.

March 06, 2020

Sarah Lipp is awarded an Indiana CTSI Predoctoral Fellowship!

This is a well deserved award for her work investigating the role of the ECM during kidney development.

March 04, 2020

Alex succesfully defends his master's thesis - congratulations!

Excellent job describing how perlecan knockdown affect the proteome of developing cartilage!

January 05, 2020

Aya is recognized as a "shooting star" at CMBE 2020!

She gave a great talk on "Probing the Dynamics of Extracellular Matrix Proteins in the Developing Mouse" in beautiful Puerto Rico.

November 22, 2019

Kaitlin's paper is accepted for publication in Connective Tissue Research!

A collaborative review with the Neu Lab

November 14, 2019

Alita travels to CA to present her research at ABRCMS 2019!

November 08, 2019

Sarah Lipp gave an excellent talk at ASN Kidney week!

Work done with our great collaborators David Hains and Andrew Schwaderer @IUSM: Mass spectrometric analysis of the extracellular matrix during renal development

August 09, 2019

Aya's paper is accepted in CMBE!

Dynamics of non-canonical amino acid-labeled intra- and extracellular proteins in the developing mouse

August 06, 2019

Ye's collaboration with the Huang lab can now be found on bioRxiv

"Three dimensional nanoscopy of whole cells and tissues with in situ point spread function retrieval" used to look at the extracellular matrix of cartilage! Thank you for including us in your study (and for showing a similar appreciation of the ECM), Fang!

August 01, 2019

Emmarie wraps up her SURF summer with a great poster presentation!

Thank you, Emmarie, for your help in the MEML this summer!

July 26, 2019

Sarah Lipp is awarded an ICT Fellowship!

The Innovation for Clinical Translation (ICT) Fellowship program was established as a key component of the expanding partnership between the Purdue College of Engineering and Indiana University School of Medicine to increase the number of doctoral engineering students who are focused on translating innovating technologies to clinical practice.

June 10, 2019

Julian starts his Master's studies in the MEML - Welcome to graduate school!

June 01, 2019

MEML collaborator, Adrian Buganza-Tepole, is awarded a grant from the NSF!

We are excited to help the Buganza Lab solve "Multiscale Mechanobiology of Growth and Remodeling During Wound Healing"

May 30, 2019

Aya is awarded a Truitt Fellowship! Congratulations!

The Truitt Fellowship is for Weldon School of Biomedical Engineering graduate students demonstrating superior academic achievements and scholarly abilities.

May 13, 2019

Alita graduates and continues her studies as a master's student! Congratulations on the promotion!

April 23, 2019

Andrea is recognized for her contributions to BME with an Outstanding Service Scholarship! Congratulations!

The Outstanding Service Scholarship recipients were selected by faculty in their School for their contributions to the quality, reputation, or success of the graduate student community, School, College, and/or University. Andrea was presented with the award at the CoE Awards Luncheon.

April 11, 2019

Aya and Tami's paper is accepted as part of the Journal of Biological Engineering's Emerging Leaders special issue!

It was great working with you, as well as Kristen and Brad from the Bundy Biotech Lab @ BYU. Congrats to all!

February 28, 2019

Roy's paper is accepted for publication in the Journal of Biomechanical Engineering!

Computational Modeling of Developing Cartilage Using Experimentally Derived Geometries and Compressive Moduli

Thank you Eric and the HIRRT lab for your support and feedback!

February 24, 2019

Andrea's paper is accepted at Experimental Mechanics! Great work Andrea and Sydney!

In situ measurement of native extracellular matrix strain

January 28, 2019

Tanaya's paper is accepted for publication at Acta Biomaterialia! Congratulations!

Incorporation of types I and III collagen in tunable hyaluronan hydrogels for vocal fold tissue engineering


A collaborative effort with the Sivasankar and Panitch labs

December 20, 2018

Yue and Andrea are awarded Bilsland Fellowships!

The Bilsland Dissertation Fellowship, which is awarded by the Dean of the Graduate School, provides support to outstanding PhD candidates in the final year of doctoral degree completion. 

December 17, 2018

Andrea, Aya and Yue are all PhD candidates: Congratulations on passing your prelim exams!

November 19, 2018

Congrats to Juan Martin for getting his paper accepted in Acta Biomaterialia!

Functionalization of hyaluronic acid hydrogels with ECM-derived peptides to control myoblast behavior

September 10, 2018

Andrea's back from her summer internship at AMGEN in South San Fransisco!

Andrea's work focused on using image analysis to study the 3D spatial distriubtion of tumor infiltrating lymphocytes in a mouse model.

August 17, 2018

Yue's paper is accepted for publication in Matrix Biology!

Hyaluronic Acid, CD44 and RHAMM regulate myoblast behavior during embryogenesis

thank you Ammara Abdullah and Mike Wendt for the assist!

August 10, 2018

Congratulations to Alex, Kathryn and Yue for getting abstracts accepted for the ASMB conference!

2 talks + 1 poster!

August 03, 2018

Nick wins best bioenginering presentation at the SURF summer symposium!

Characterization and Quantification of Fibrin Gel Mechanics with Fibroblast Invasion - In collaboration with Adrian Buganza-Tepole in ME

July 12, 2018

Dr. Calve presents biomechanics of musculoskeletal development

Title of talk at the World Congress of Biomechanics 2018 - "Chondrocyte stiffness increases in tandem with matrix stiffness during development to maintain a constant intracellular strain"

July 08, 2018

Andrea travels to Ireland to present her research on In Situ Measurement of ECM Strain

World Congress of Biomehcanics in Dublin; July 8th - July 14th, 2018

July 06, 2018

Juan Martin successfully defends his master's thesis!

Functionalization of hyaluronic acid hydrogels with ECM-derived peptides to control myoblast behavior

July 02, 2018

Sarah Lipp joins the MEML as part of the MSTP in Biomedical Engineering

Welcome Sarah! 

June 18, 2018

Dr. Calve participates in National Academy of Engineering's JAFOE 2018

April 06, 2018

Alex Ocken wins 2018 BME-IBSc-PI4D Research Symposium Poster Presentation

Award presented in category for Biomaterials, Biomechanics, and Tissue Engineering for poster titled: Quantifying Extracellular Matrix Protein Turnover In Vivo During Wound Healing. 

February 01, 2018

Ye Bu joins MEML as a Post Doctoral Research Fellow

January 03, 2018

Dr. Calve awarded the Rising Star Award for Junior Faculty

Sarah Calve, an assistant professor in Purdue's Weldon School of Biomedical Engineering, has been named the recipient of the 2018 Rising Star Award for Junior Faculty from the Biomedical Engineering Society (BMES) at the Cellular and Molecular Bioengineering (CMBE) Conference on Jan. 3, in Key Largo, FL. The theme of this year’s conference was Transformative and Translational Mechanobiology.

December 01, 2018

Michael Walls begins his role as Research Associate in MEML

November 28, 2017

Andrea Acuña awarded the Ronald W. Dollens Graduate Scholarship

Andrea Acuña is a recipient of the Ronald W. Dollens Scholarship for 2017-2018. The scholarship is a joint award between the Weldon School of Biomedical Engineering and the College of Pharmacy, and is awarded based on academic merit to deserving PhD students in these schools who are performing research in the areas of cardiovascular devices, implantable biomaterials design, drug-delivery systems, or biochemical sensors.

September 30, 2017

MEML receives DP2 for Defining the Mechanical Link that Unites the Musculoskeletal System during Limb Development

Sarah Calve, assistant professor at Purdue's Weldon School of Biomedical Engineering, received the National Institutes of Health Director's New Innovator Award. The High-Risk, High-Reward Research Program award supports exceptionally creative scientists using highly innovative approaches to tackle major challenges in biomedical research. the musculoskeletal system from being primarily structural to one that is also instructive.

September 01, 2017

MEML receives R01 for Biomechanical Influence of ECM Remodeling on the Developing Enthesis

Our objective is to determine the composition, structure and mechanical properties of the extracellular matrix in the developing enthesis. The innovation of this proposal is the combination of bioorthogonal labeling, 3D imaging and atomic force microscopy-based mechanical analyses of viable murine tissues to characterize the developing enthesis as a function of development and embryonic motility. By characterizing the environment that facilitates enthesis assembly in vivo, the design of scaffolds and other regenerative therapies will be better informed and ultimately more successful.

August 01, 2017

Chenwei Duan joins MEML as a Graduate Research Assistant

July 01, 2016

MEML receives Showalter Trust award

Calve’s award will fund her research project entitled: “Design of 3D Hydrogels for the Treatment of Volumetric Muscle Loss.” The objective of this project is to identify and characterize hydrogel-peptide combinations that foster scar-free muscle repair after injury. 

April 01, 2016

MEML Receives R21 for Bioorthogonal Labeling of Extracellular Matrix Assembly

Our objective is to metabolically label the extracellular matrix in developing tissues to identify key components and their rate of turnover. The innovation of this proposal is the combination of novel 3D imaging techniques and mass spectroscopy with bioorthogonal labeling of murine tissues in vivo to obtain a 4D map of ECM remodeling in the developing limb. By characterizing the environment that facilitates tissue assembly in vivo, the design of artificial scaffolds and other regenerative therapies will be better informed and ultimately more successful.

January 26, 2017

Alexander Ocken gets promoted

Alex Ocken joined the MEML as an undergrad in the Fall of 2015 and was instrumental in laying the groundwork for our non-canonical amino acid studies. We are happy that Alex decided to continue his graduate studies with the MEML, becoming a PhD student as of January 2017.

October 02, 2016

BMES podium presentations

Congrats to Andrea Acuna and Michael Drakopoulos for having their abstracts chosen for podium presentations at BMES 2016

Measurement of Displacement Fields of Native Extracellular Matrix Fibrils Loaded In Situ

Andrea Acuna
Michael Drakopoulos
Benjamin Sather
Craig Goergen 
Sarah Calve 

A Method to Characterize Extracellular Matrix Composition and 3D Structure During Embryonic Development

Michael Drakopoulos

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